121706-11-4 Usage
Description
(2S,5S)-9-hexyl-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one is a complex chemical compound belonging to the diazoninoindolone class. It features a hexyl side chain and a hydroxymethyl group, giving it a distinctive molecular structure. This white solid is of interest in pharmaceutical and chemical research due to its potential biological activity and unique structural features. Further investigation is required to explore its properties and possible applications across different fields.
Uses
Used in Pharmaceutical Research:
(2S,5S)-9-hexyl-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one is used as a subject of study in pharmaceutical research for its potential biological activity. Its unique structure may offer new avenues for the development of therapeutic agents.
Used in Chemical Research:
In the field of chemical research, (2S,5S)-9-hexyl-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one serves as a compound of interest for understanding its reactivity, synthesis, and potential role in the creation of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 121706-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,7,0 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 121706-11:
(8*1)+(7*2)+(6*1)+(5*7)+(4*0)+(3*6)+(2*1)+(1*1)=84
84 % 10 = 4
So 121706-11-4 is a valid CAS Registry Number.
121706-11-4Relevant articles and documents
Synthesis, conformation and PKC isozyme surrogate binding of indolinelactam-Vs, new conformationally restricted analogues of (-)-indolactam-V
Nakagawa, Yu,Irie, Kazuhiro,Komiya, Yusuke,Ohigashi, Hajime,Tsuda, Ken-Ichiro
, p. 7077 - 7084 (2004)
New conformationally restricted analogues of tumor promoter (-)-indolactam-V (1), indolinelactam-Vs (8, 11) and their hexyl derivatives at position 1 or 7 (9, 10, 12, 13), were synthesized from 1. (3R)-Indolinelactam-V (8) adopted a conformation similar to the twist form of 1 with a cis amide, while the conformation of (3S)-indolinelactam-V (11) was close to that of the sofa form of 1 with a trans amide. 7-Hexyl derivatives of 8 and 11 (10, 13) showed binding affinities for C1 domains of protein kinase C (PKC) isozymes compared to 1, but exhibited little selectivity among these PKC isozymes. However, introduction of the hexyl group at position 1 of 8 and 11 significantly enhanced their binding selectivity for novel PKC isozymes. The best selectivity for novel PKC isozymes was observed in (3S)-1-hexylindolinelactam-V (12) with a sofa-like conformation. These results suggest that a sofa-restricted analogue of 1 with a hydrophobic chain at an appropriate position would be a promising lead for designing agents with a high selectivity for novel PKC isozymes.
Synthetic chemistery, neurotransmission and second messengers
Kozikowski
, p. 97 - 105 (2007/10/02)
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