1217310-02-5

Basic information

• Product Name: 2-amino-4-(4-(2-phenoxyethyl)piperazin-1-yl)-6-phenylthieno[2,3-d]pyrimidine
• CAS NO: 1217310-02-5
• Molecular Weight: 431.561
• Mol File: 1217310-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-4-(4-(2-phenoxyethyl)piperazin-1-yl)-6-phenylthieno[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(4-(2-phenoxyethyl)piperazin-1-yl)-6-phenylthieno[2,3-d]pyrimidine(1217310-02-5)
• EPA Substance Registry System: 2-amino-4-(4-(2-phenoxyethyl)piperazin-1-yl)-6-phenylthieno[2,3-d]pyrimidine(1217310-02-5)

Safety Data

• Hazardous Substances Data: 1217310-02-5(Hazardous Substances Data)

Upstream product

• 13484-37-2 1-[2-phenoxyethyl]piperazine 
• 1216257-25-8 2-amino-6-phenyl-thieno[2,3-d]pyrimidin-4(3H)-one 

Relevant articles and documents

Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues

The synthesis of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidines is described. The synthetic route allows introducing structural variety at positions 2, 4 and 6 of the scaffold. Evaluation of their immunosuppressive activity in a Mixed Lymphocyte Reaction (MLR) assay revealed that the most potent compound has an IC50-value of 66 nM and therefore deserves attention for further medicinal chemistry optimization.