12174-11-7 Usage
Description
ATTAPULGITE, also known as Palygorskite or Fuller's Earth, is a hydrated aluminum-magnesium silicate mineral. It is characterized by its light cream-colored, very fine powder appearance with particle size ranges varying depending on the grade and manufacturer. ATTAPULGITE is known for its solid chemical properties and is widely used in various industries due to its unique characteristics.
Uses
Used in Animal Care Industry:
ATTAPULGITE is used as an excipient for the production of animal waste absorbents, particularly in cat litter. Its absorbent properties make it an ideal choice for managing animal waste effectively.
Used in Oil and Gas Industry:
ATTAPULGITE is used as a component of drilling muds in the oil and gas industry. Its ability to absorb oil and grease makes it a valuable additive for enhancing the performance of drilling muds.
Used in Environmental Applications:
ATTAPULGITE is used as an oil and grease absorbent in environmental applications. Its high absorption capacity helps in cleaning up oil spills and managing grease-related contamination.
Used in Agriculture:
ATTAPULGITE is used in fertilizer and pesticide formulations in the agricultural industry. Its properties contribute to improving soil structure and nutrient retention, thereby enhancing crop growth and yield.
Production Methods
Attapulgite occurs naturally as the mineral palygorskite.
Hazard
Possible carcinogen.
Pharmaceutical Applications
Attapulgite is widely used as an adsorbent in solid dosage forms.
Colloidal clays (such as attapulgite) absorb considerable amounts of
water to form gels and in concentrations of 2–5% w/v usually form
oil-in-water emulsions. Activated attapulgite, which is attapulgite
that has been carefully heated to increase its absorptive capacity, is
used therapeutically as an adjunct in the management of diarrhea.
Safety Profile
Suspected carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety
Attapulgite is widely used in pharmaceutical formulations and is
generally regarded as an essentially nontoxic and nonirritant
material. It is not absorbed following oral administration. In oral
preparations, activated attapulgite up to 9 g is used in daily divided
doses as an adjunct in the management of diarrhea.
storage
Attapulgite can adsorb water. It should be stored in an airtight
container in a cool, dry, location.
Incompatibilities
Attapulgite may decrease the bioavailability of some drugs such as
loperamide and riboflavin. Oxidation of hydrocortisone is
increased in the presence of attapulgite.
Regulatory Status
Included in nonparenteral medicines licensed in a number of
countries worldwide including the UK and USA.
Check Digit Verification of cas no
The CAS Registry Mumber 12174-11-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,1,7 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 12174-11:
(7*1)+(6*2)+(5*1)+(4*7)+(3*4)+(2*1)+(1*1)=67
67 % 10 = 7
So 12174-11-7 is a valid CAS Registry Number.
InChI:InChI=1/Al.Mg.O3Si/c;;1-4(2)3/q+3;+2;-2