121743-00-8

Basic information

• Product Name: 2-(2-methyl-3-phenylallylidene)succinic acid 1-methyl ester
• Synonyms: 2-(2-methyl-3-phenylallylidene)succinic acid 1-methyl ester
• CAS NO: 121743-00-8
• Molecular Weight: 260.29
• Mol File: 121743-00-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2-methyl-3-phenylallylidene)succinic acid 1-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methyl-3-phenylallylidene)succinic acid 1-methyl ester(121743-00-8)
• EPA Substance Registry System: 2-(2-methyl-3-phenylallylidene)succinic acid 1-methyl ester(121743-00-8)

Safety Data

• Hazardous Substances Data: 121743-00-8(Hazardous Substances Data)

Upstream product

• 121742-93-6 t-butyl 3-methoxycarbonyl-5-methyl-6-phenylhexa-3,5-dienoate 
• 15174-47-7 α-methyl-trans-cinnamaldehyde 
• 106-65-0 Dimethyl succinate 
• 57367-56-3 2-tert-Butoxycarbonyl-1-methoxycarbonylethylidene(triphenyl)phosphorane 

Downstream Products

• 121743-11-1 2-methoxycarbonyl-4-methyl-5-phenylpenta-2,4-dienylamine p-toluenesulphonate 
• 206061-44-1 Benzoic acid 2-acetyl-1-oxo-tetrahydro-1λ⁴-thiophen-3-ylmethyl ester 
• 206061-45-2 benzoic acid 2-acetyltetrahydrothiophen-3-ylmethyl ester 
• 206061-46-3 1-(3-hydroxymethyl-tetrahydrothiophen-2-yl)ethanone 
• 26693-24-3 6-methyl-2,3-dihydrothieno[2,3-c]furan 

Relevant articles and documents

Synthesis of 2,3-Dihydro-6-methylthienofuran (Kahweofuran), a Coffee Aroma Component, from an Acyclic Precursor

Kahweofuran 1, one of the impact flavours of roasted coffee, was obtained from the acyclic unsaturated ester 8, produced in a Stobbe condensation of α-methylcinnamaldehyde 6 with dimethyl succinate 7, through the key intermediate tetrahydrothiophene 14 and the C-7 derivatives 20 or 24, respeectively.

SYNTHESIS OF SUBSTITUTED TETRAHYDROPYRIDINES AND M-HYDROXYBENZOIC ACIDS

A series of substituted 1,2,3,6- (5) and 1,2,5,6-tetrahydropyridines (6) have been synthesised via intramolecular 1,6-Michael addition of methoxycarbonyl-2,4-dienylamines (10).The kinetics of these reactions have been investigated and an explanation of substituent effects is advanced.Also a new route to m-hydroxybenzoic acids has been established by cyclisation of substituted hexa-3,4:5,6-dienoic acids.