1219468-79-7Relevant articles and documents
Conception and evolution of stereocontrolled strategies toward functionalized 8-aryloctanoic acids related to the total synthesis of aliskiren
Hanessian, Stephen,Chnard, Etienne,Guesn, Sbastien,Cusson, Jean-Philippe
, p. 9531 - 9545 (2015/02/19)
A detailed account is given describing the approaches used toward the total synthesis of aliskiren. In particular, ring-closing metathesis with the Hoveyda-Grubbs catalyst accelerates the formation of a 9-membered lactone from an (R)-ester. The diastereom