1219802-19-3 Usage
Description
N,N-Dimethyl-d3-chloroacetamide, also known as N-methyl-d3, is an isotopically labeled research compound with the CAS number 1219802-19-3. It is a derivative of chloroacetamide, featuring a deuterium atom (D) in the N-methyl group, which distinguishes it from its non-isotopic counterpart. N,N-Dimethyl-d3-chloroacetamide is primarily utilized in scientific research and development, particularly in the fields of chemistry and biochemistry.
Uses
Used in Chemical Synthesis:
N,N-Dimethyl-d3-chloroacetamide is used as an isotopically labeled reagent for chemical synthesis. The incorporation of deuterium in the molecule allows researchers to track the behavior and fate of the compound within chemical reactions, providing valuable insights into reaction mechanisms and pathways.
Used in Biochemical Research:
In the field of biochemistry, N,N-Dimethyl-d3-chloroacetamide is employed as a labeled compound for studying enzyme kinetics and metabolic pathways. The presence of deuterium can help researchers differentiate between the labeled compound and its non-isotopic analogs, enabling the investigation of enzyme specificity and substrate selectivity.
Used in Pharmaceutical Development:
N,N-Dimethyl-d3-chloroacetamide is also used in the development of new pharmaceuticals. The isotopically labeled compound can be used to study the pharmacokinetics and pharmacodynamics of drug candidates, as well as to identify potential metabolic pathways and metabolites. This information is crucial for the optimization of drug design and the assessment of drug safety and efficacy.
Used in Analytical Chemistry:
In analytical chemistry, N,N-Dimethyl-d3-chloroacetamide serves as an internal standard or reference compound for various analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The presence of deuterium in the molecule can improve the accuracy and precision of these analytical methods, allowing for more reliable quantification and identification of target compounds.
Used in Environmental Studies:
N,N-Dimethyl-d3-chloroacetamide can be utilized in environmental research to study the fate and transport of pollutants in the environment. The isotopically labeled compound can be used as a tracer to monitor the behavior of pollutants in soil, water, and air, providing valuable information on their degradation, transformation, and potential impact on ecosystems.
Check Digit Verification of cas no
The CAS Registry Mumber 1219802-19-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,8,0 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1219802-19:
(9*1)+(8*2)+(7*1)+(6*9)+(5*8)+(4*0)+(3*2)+(2*1)+(1*9)=143
143 % 10 = 3
So 1219802-19-3 is a valid CAS Registry Number.
1219802-19-3Relevant articles and documents
A novel five-lipoxygenase activity protein inhibitor labeled with carbon-14 and deuterium
Latli, Bachir,Hrapchak, Matt,Gao, Joe J.,Busacca, Carl A.,Senanayake, Chris H.
, p. 390 - 394 (2015)
2-[4-(3-{(1R)-1-[4-(2-Aminopyrimidin-5-yl)phenyl]-1-cyclopropylethyl}-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl]-N,N-dimethylacetamide (1), is a novel and selective five-lipoxygenase activity protein (FLAP) inhibitor with excellent pharmacokinetics properties
