122078-14-2Relevant articles and documents
ENANTIOMERICALLY PURE OXYGENATED 1-PHENYLETHYLAMINES FROM SUBSTITUTED ACETOPHENONES: BY REDUCTIVE AMINATION AND REGIOSPECIFIC CLEAVAGE
Bringmann, Gerhard,Geisler, Joerg-Peter
, p. 317 - 320 (2007/10/02)
An efficient method for the asymmetric synthesis of chiral, oxygenated 1-phenylethylamines (1) in essentially two steps is described.The substituted acetophenones 2 are reductively aminated with unsubstituted chiral 1-phenylethylamine ("PEA",3), via the c