1221-79-0

Basic information

• Product Name: 4(3H)-Quinazolinone, 2-methyl-3-(phenylamino)-
• CAS NO: 1221-79-0
• Molecular Formula: C15H13N3O
• Molecular Weight: 251.288
• Mol File: 1221-79-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4(3H)-Quinazolinone, 2-methyl-3-(phenylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 2-methyl-3-(phenylamino)-(1221-79-0)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 2-methyl-3-(phenylamino)-(1221-79-0)

Safety Data

• Hazardous Substances Data: 1221-79-0(Hazardous Substances Data)

Upstream product

• 118-92-3 anthranilic acid 
• 118-48-9 isatoic anhydride 
• 78-39-7 Triethyl orthoacetate 
• 100-63-0 phenylhydrazine 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 89-52-1 o-acetylamino-benzoic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 91155-19-0 Co(C₈H₄N₂O(CH₃)NHC₆H₅)2(CH₃CO₂)2 
• 91155-21-4 Cd(C₈H₄N₂O(CH₃)NHC₆H₅)(CH₃CO₂)2 
• 91155-20-3 Zn(C₈H₄N₂O(CH₃)NHC₆H₅)(CH₃CO₂)2 
• 106756-12-1 RuCl₂(C₈H₄N₂O(CH₃)(NHC₆H₅))2 
• 91155-18-9 Ni(C₈H₄N₂O(CH₃)NHC₆H₅)2Cl₂ 
• 85226-40-0 2-[(E)-2-(4-Methoxy-phenyl)-vinyl]-3-phenylamino-3H-quinazolin-4-one 

Relevant articles and documents

Conjugate addition from the excited state

Conjugate addition occurs efficiently from excited hydrazide based acrylanilides under both UV and metal free visible light irradiations. The reaction proceeds via an excited state encounter complex that bifurcates either via an electron or energy transfer pathway. The generality of excited state conjugate addition is demonstrated using chloromethylation and by thiol addition.

Design, synthesis and antibacterial evaluation of 2-alkyl- and 2-aryl-3-(phenylamino)quinazolin-4(3H)-one derivatives

2-Alkyl and 2-aryl-3-(phenylamino)quinazolin-4(3H)-ones 4a-h were synthesized in a one-pot three-component condensation of an isatoic anhydride 1a-h, ethyl or methyl ortho ester and phenylhydrazine in the presence of KAl(SO4)2·12H2O (alum) as a nontoxic, reusable, inexpensive and easily available catalyst. The synthesis was conducted under microwave irradiation or classical heating. Products 4a and 4b show good antimicrobial activities.

SUBSTITUTED 4-QUINAZOLINONE DERIVATIVES AS HYPNOTICS AND

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