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1221403-24-2

1221403-24-2

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1221403-24-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1221403-24-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,4,0 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1221403-24:
(9*1)+(8*2)+(7*2)+(6*1)+(5*4)+(4*0)+(3*3)+(2*2)+(1*4)=82
82 % 10 = 2
So 1221403-24-2 is a valid CAS Registry Number.

1221403-24-2Downstream Products

1221403-24-2Relevant articles and documents

Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity

Yu, Ming,Lizarzaburu, Mike,Beckmann, Holger,Connors, Richard,Dai, Kang,Haller, Katrin,Li, Cong,Liang, Lingming,Lindstrom, Michelle,Ma, Ji,Motani, Alykhan,Wanska, Malgorzata,Zhang, Alex,Li, Leping,Medina, Julio C.

scheme or table, p. 1758 - 1762 (2010/07/05)

Piperazine-bisamide analogs were discovered as partial agonists of human growth hormone secretagogue receptor (GHSR) in a high throughput screen. The partial agonists were optimized for potency and converted into antagonists through structure-activity relationship (SAR) studies. The efforts also led to the identification of potent antagonist with favorable PK profile suitable as a tool compound for in vivo studies.

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