122628-38-0Relevant articles and documents
Design and evolution of copper apatite catalysts for N-arylation of heterocycles with chloro- and fluoroarenes
Choudary, Boyapati M.,Sridhar, Chidara,Kantam, Mannepalli L.,Venkanna, Gopaldasu T.,Sreedhar, Bojja
, p. 9948 - 9949 (2005)
We report the preparation of recyclable heterogeneous catalysts, copper-exchanged fluorapatite, and copper-exchanged tert-butoxyapatite by incorporating basic species F-/tBuO- in apatite in situ by coprecipitation and subsequent exchange with Cu(II). These basic copper catalysts catalyzed N-arylation of imidazoles and other heterocycles with chloroarenes and electron-poor fluoroarenes in good to excellent yields. Synthesis and characterization of some of the intermediates of the catalytic cycle gave some insight into the mechanism of the very important organic transformation. The necessity of basic sites for the activation of C-Cl and C-F bonds in the N-arylation of heterocycles with haloarenes is well-established. Copyright
N-arylation of heterocycles with activated chloro- and fluoroarenes using nanocrystalline copper(II) oxide
Kantam, M. Lakshmi,Yadav, Jagjit,Laha, Soumi,Sreedhar, Bojja,Jha, Shailendra
, p. 1938 - 1942 (2008/09/16)
Nanocrystalline copper oxide was found to be an effective heterogeneous catalyst for the N-arylation of heterocycles with activated chloro- and fluoroarenes using potassium carbonate as base. N-Arylated products were isolated in good to excellent yields. The catalyst can be used for five cycles with almost consistent activity.
