1227926-30-8

Basic information

• Product Name: 2-hydroxy-8-methyl-4H-pyrimido[1,2-a]pyrimidin-4-one
• Synonyms: 2-hydroxy-8-methyl-4H-pyrimido[1,2-a]pyrimidin-4-one
• CAS NO: 1227926-30-8
• Molecular Weight: 177.162
• Mol File: 1227926-30-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-8-methyl-4H-pyrimido[1,2-a]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-8-methyl-4H-pyrimido[1,2-a]pyrimidin-4-one(1227926-30-8)
• EPA Substance Registry System: 2-hydroxy-8-methyl-4H-pyrimido[1,2-a]pyrimidin-4-one(1227926-30-8)

Safety Data

• Hazardous Substances Data: 1227926-30-8(Hazardous Substances Data)

Upstream product

• 108-52-1 4-Methyl-pyrimidin-2-ylamin 
• 15781-70-1 malonic acid bis-(2,4,6-trichloro-phenyl) ester 

Relevant articles and documents

Facile synthesis of novel pyrimido[1,2-a]pyrimidin-4-ones from highly reactive malonates

A very simple and efficient procedure for the synthesis of novel 2-hydrox.y-4H-pyrimido[1,2-a]pyrimidin-4-ones is described. Title compounds were obtained from the room temperature reaction of 2-aminopyrimidine and its substituted derivatives with bis(2,4,6-trichlorophenyl) malonates. High product yields were observed under optimized conditions. Applicability and reactivity of a range of substituted and unsubstituted phenyl malonates were also investigated. Structural identification of all new compounds was accomplished by spectroscopic methods and elemental analysis.