1228284-86-3

Basic information

• Product Name: 1-(2,4,6-trichlorophenyl)propan-2-one
• Synonyms: 1-(2,4,6-trichlorophenyl)propan-2-one
• CAS NO: 1228284-86-3
• Molecular Weight: 237.513
• Mol File: 1228284-86-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 296℃ at 102.3-103.1kPa
• Density: 1.53 at 21℃
• CAS DataBase Reference: 1-(2,4,6-trichlorophenyl)propan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4,6-trichlorophenyl)propan-2-one(1228284-86-3)
• EPA Substance Registry System: 1-(2,4,6-trichlorophenyl)propan-2-one(1228284-86-3)

Safety Data

• Hazardous Substances Data: 1228284-86-3(Hazardous Substances Data)

Usage

Description

1-(2,4,6-trichlorophenyl)propan-2-one is an organic compound that serves as a crucial intermediate in the synthesis of various chemical compounds, particularly in the production of carboxamide-based plant growth enhancers.

Uses

Used in Agricultural Industry:
1-(2,4,6-trichlorophenyl)propan-2-one is used as an intermediate in the synthesis of Pydiflumetofen (P999040), a compound that is utilized in the preparation of carboxamides. These carboxamides function as plant growth enhancers, promoting healthy growth and development in crops. This application contributes to increased agricultural productivity and crop quality.

Upstream product

• 1228284-88-5 1,3,5-trichloro-2-((E)-2-nitro-propenyl)-benzene 
• 7439-89-6 iron 
• 24473-00-5 2,4,6-trichlorobenzaldehyde 
• 108-22-5 Isopropenyl acetate 
• 634-93-5 2,4,6-trichloroaniline 
• 5586-88-9 1-(4-chlorophenyl)propan-2-one 
• 106-47-8 4-chloro-aniline 
• 23749-65-7 2,4,6-trichlorotoluene 

Downstream Products

• 1228284-89-6 1-(2,4,6-trichlorophenyl)propan-2-one O-methyloxime 
• 1228284-64-7 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid methoxy-[1-methyl-2-(2,4,6-trichloro-phenyl)-ethyl]-amide 
• 1228284-78-3 O-methyl-N-[1-methyl-2-(2,4,6-trichloro-phenyl)-ethyl]-hydroxylamine 
• 1452295-74-7 (E)-1-(2,4,6-trichlorophenyl)propan-2-one O-methyloxime 
• 1452295-76-9 (Z)-1-(2,4,6-trichlorophenyl)propan-2-one O-methyloxime 

Relevant articles and documents

Preparation method of 2, 4, 6-trichlorophenyl substituted acetone

The invention relates to a preparation method of 2, 4, 6-trichlorophenyl substituted acetone, which comprises the following steps: adding 2, 4, 6-trichlorotoluene and a chlorination reagent into an organic solvent at a certain temperature to prepare 2, 4, 6-trichlorophenyl benzyl chloride, then coupling with ethynyl magnesium halide under the action of a metal catalyst, and then carrying out acid catalysis and water addition to finally obtain the product 2, 4, 6-trichlorophenyl substituted acetone. The method provided by the invention has the advantages of many raw material sources, obvious cost advantage, safer and more convenient preparation method, high total yield and less three wastes, and is beneficial to industrialization.

PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLPROPANONES

The invention relates to a process for the preparation of a compound of formula (I) wherein the substituents are defined as in claim 1, which process comprises adding a compound of formula (II), wherein R1, R2 and R3 have the meanings as described under formula (I), in the presence of an inert organic solvent, to a mixture comprising an organic nitrite of formula (III) R4—O—N═O, wherein R4 is C1-C8alkyl, a compound of formula (IV), and an inert organic solvent.

PROCESS FOR THE PREPARATION OF PHENYL SUBSTITUTED 3 - DIFLUOROMETHYL - 1 -METHYL - 1H - PYRAZOLE - 4 - CARBOXYLIC N-METHOXY- [1 -METHYL- 2 - PHENYLETHYL] AMIDES

The invention relates to a process for the preparation of a compound of formula (I), wherein R1, R2 and R3 are as defined in claim 1, which process comprises a) adding a compound of formula (II), in the presence of an inert organic solvent to a mixture comprising an organic nitrite of formula (III) (R4-O-N=O (III)), wherein R4 is C1-C8alkyl, a compound of formula (IV), and an inert organic solvent; b) reacting the resulting compound of formula (V), with H2N-O-CH3 to the compound of formula (VII), c) reducing the compound of formula (VII) to the compound of formula (VIII), d) and reacting the compound of formula VIII with a compound of formula (IX), in which R* is halogen, hydroxy or C1-6 alkoxy, to the compound of formula (I).