123094-61-1

Basic information

• Product Name: 6-(BENZYLOXY)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE
• Synonyms: 6-(BENZYLOXY)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE;6-(benzyloxy)chroman-4-one
• CAS NO: 123094-61-1
• Molecular Weight: 254.285
• Mol File: 123094-61-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6-(BENZYLOXY)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(BENZYLOXY)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE(123094-61-1)
• EPA Substance Registry System: 6-(BENZYLOXY)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE(123094-61-1)

Safety Data

• Hazardous Substances Data: 123094-61-1(Hazardous Substances Data)

Upstream product

• 80096-64-6 6-hydroxy-2,3-dihydro-4H-chromen-4-one 
• 100-39-0 benzyl bromide 
• 103-16-2 4-Benzyloxyphenol 
• 584-08-7 potassium carbonate 
• 5802-17-5 6-methoxychroman-4-one 

Downstream Products

• 251639-70-0 3-{6-benzyloxy-4-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionyloxy]-chroman-3-ylmethyl}-4-methoxy-benzoic acid methyl ester 
• 158102-93-3 CP-199,331 
• 251639-71-1 [3-((3R,4R)-6-Benzyloxy-4-hydroxy-chroman-3-ylmethyl)-4-methoxy-phenyl]-carbamic acid benzyl ester 
• 251639-72-2 (3R,4R)-3-(5-Amino-2-methoxy-benzyl)-6-(7-chloro-quinolin-2-ylmethoxy)-chroman-4-ol 
• 158102-89-7 3-((3R,4R)-6-Benzyloxy-4-hydroxy-chroman-3-ylmethyl)-4-methoxy-benzoic acid 
• 158102-86-4 3-(6-Benzyloxy-4-oxochroman-3-ylmethyl)-4-methoxybenzoic acid methyl ester 
• 158102-91-1 (3R,4R)-3-(5-Amino-2-methoxy-benzyl)-chroman-4,6-diol 

Relevant articles and documents

Synthesis of Flavanones via Palladium(II)-Catalyzed One-Pot β-Arylation of Chromanones with Arylboronic Acids

A total of 47 flavanones were expediently synthesized via one-pot β-arylation of chromanones, a class of simple ketones possessing chemically unactivated β sites, with arylboronic acids via tandem palladium(II) catalysis. This reaction provides a novel route to various flavanones, including natural products such as naringenin trimethyl ether, in yields up to 92percent.

Discovery of CP-199,330 and CP-199,331: Two potent and orally efficacious cysteinyl LT1 receptor antagonists devoid of liver toxicity

CP-199,330 (3) and CP-199,331 (4) are cysLT1 receptor antagonists that are equipotent to marketed cysLT1 receptor antagonists zafirlukast and pranlukast, show good pharmacokinetics in rats and monkeys, and are devoid of liver toxicity in monkeys as seen in CP-85,958 (1).

SUBSTITUTED CHROMANS AND THEIR USE IN THE TREATMENT OF ASTHMA, ARTHRITIS AND RELATED DISEASES

Substituted chromans which by inhibiting 5-lipoxygenase enzyme are useful in the prevention or treatment of asthma, arthritis, psoriasis, ulcers, myocardial infarction, stroke and related disease states in mammals, pharmaceutical compositions thereof, a m