1231257-90-1

Basic information

• Product Name: N-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
• Synonyms: N-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
• CAS NO: 1231257-90-1
• Molecular Weight: 275.156
• Mol File: 1231257-90-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide(1231257-90-1)
• EPA Substance Registry System: N-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide(1231257-90-1)

Safety Data

• Hazardous Substances Data: 1231257-90-1(Hazardous Substances Data)

Upstream product

• 579-10-2 N-acetyl-N-methylaniline 
• 73183-34-3 bis(pinacol)diborane 
• 100-61-8 N-methylaniline 
• 480424-93-9 N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide 
• 74-88-4 methyl iodide 

Downstream Products

• 1227719-66-5 N-methyl-N-(3-(6-(3-(trifluoromethoxy)phenylamino)pyridin-3-yl)phenyl)acetamide 
• 1231257-67-2 N-methyl-N-(3-(8-(3-(trifluoromethyl)phenylamino)imidazo[1,2-a]pyrazin-3-yl)phenyl)acetamide 

Relevant articles and documents

Amide Effects in C?H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides

A new concept for the meta-selective borylation of aromatic amides is described. It has been demonstrated that while esters gave para borylations, amides lead to meta borylations. For achieving high meta selectivity, an L-shaped bifunctional ligand has been employed and engages in an O???K noncovalent interaction with the oxygen atom of the moderately distorted amide carbonyl group. This interaction provides exceptional control for meta C?H activation/borylation.

COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY

Compounds of formula (I): wherein R1, R2, X1, and X2 are as defined herein, are useful for the treatment or prophylaxis of conditions such as Duchenne muscular dystrophy, Becker muscular dystrophy, and cachexia.