123314-39-6 Usage
Description
H-CIT-AMC HBR, also known as H-L-Cit-AMC Hydrobromide, is a fluorogenic substrate specifically designed for the detection and measurement of cysteine protease activity. It is a synthetic peptide derivative that, upon cleavage by cysteine proteases, releases a highly fluorescent molecule, 7-amino-4-trifluoromethylcoumarin (AMC), allowing for sensitive and quantitative assessment of enzyme activity.
Uses
Used in Research Applications:
H-CIT-AMC HBR is used as a research tool for studying the activity and function of cysteine proteases, such as papain, bromelain, and ficin. It serves as a valuable probe in various biochemical and cell biology experiments, enabling researchers to monitor enzyme activity, screen for inhibitors, and investigate the role of these enzymes in physiological and pathological processes.
Used in Drug Discovery and Development:
In the pharmaceutical industry, H-CIT-AMC HBR is employed as a screening agent for the identification and optimization of potential cysteine protease inhibitors. This is crucial for the development of new drugs targeting diseases associated with abnormal cysteine protease activity, such as cancer, neurodegenerative disorders, and inflammatory conditions.
Used in Diagnostic Applications:
H-CIT-AMC HBR can be utilized in diagnostic assays to detect and quantify cysteine protease activity in biological samples. This can be particularly useful in clinical settings for the assessment of disease progression, monitoring treatment efficacy, and predicting patient outcomes.
Used in Food Industry:
In the food industry, H-CIT-AMC HBR may be used to evaluate the activity of cysteine proteases, such as papain and bromelain, which are commonly employed as meat tenderizers and flavor enhancers. By monitoring the activity of these enzymes, food manufacturers can optimize processing conditions and ensure product quality.
Check Digit Verification of cas no
The CAS Registry Mumber 123314-39-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,3,1 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 123314-39:
(8*1)+(7*2)+(6*3)+(5*3)+(4*1)+(3*4)+(2*3)+(1*9)=86
86 % 10 = 6
So 123314-39-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H20N4O4.BrH/c1-9-7-14(21)24-13-8-10(4-5-11(9)13)20-15(22)12(17)3-2-6-19-16(18)23;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,20,22)(H3,18,19,23);1H/t12-;/m0./s1