123333-26-6Relevant articles and documents
(E)-4-(α-Halo-p-tolyl)-2-oxo-3-butenoic Acids Inhibit Yeast Pyruvate Decarboxylase by a Diversity of Mechanisms: Multiple Fate for the Thiamin-Bound Enamine Intermediate
Annan, Nikoi,Paris, Richard,Jordan, Frank
, p. 8895 - 8901 (1989)
(E)-4-(p-Tolyl)-2-oxo-3-butenoic acid and its α-(bromomethyl) and α-(chloromethyl) derivatives have been synthesized, and their interaction with brewers' yeast pyruvate decarboxylase was evaluated.The p-tolyl compound was found to be a slow substrate.The