1233764-92-5Relevant articles and documents
Synthesis of regioisomeric 17β-N-phenylpyrazolyl steroid derivatives and their inhibitory effect on 17α-hydroxylase/C17,20-lyase
Iványi, Zoltán,W?lfling, János,G?rbe, Tamás,Szécsi, Mihály,Wittmann, Tibor,Schneider, Gyula
experimental part, p. 450 - 456 (2010/06/13)
The reaction of 3β-hydroxy-21-hydroxymethylidenepregn-5-en-3β-ol-20-one (1) with phenylhydrazine (2a) affords two regioisomers, 17β-(1-phenyl-3-pyrazolyl)androst-3-en-3β-ol (5a) and 17β-(1-phenyl-5-pyrazolyl)androst-5-en-3β-ol (6a). The direction of the r