123636-86-2

Basic information

• Product Name: (S)-2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
• Synonyms: (S)-2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
• CAS NO: 123636-86-2
• Molecular Weight: 473.528
• Mol File: 123636-86-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(123636-86-2)
• EPA Substance Registry System: (S)-2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(123636-86-2)

Safety Data

• Hazardous Substances Data: 123636-86-2(Hazardous Substances Data)

Upstream product

• 141848-61-5 6-Bromomethyl-2,4-dimethyl-quinoline 
• 2243-89-2 2,4,6-trimethylquinoline 

Relevant articles and documents

Quinoline antifolate thymidylate synthase inhibitors: Variation of the C2- and C4-substituents

Modifications to the bicyclic ring system of the potent thymidylate synthase (TS) inhibitor N-[4-[N-[(2-amino-3,4-dihydro-4-oxo-6- quinazolinyl)methyl]-N-prop-2-ynylamino]benzoyl]-L-glutamic acid (1, CB3717) have led to the synthesis of a series of quinol