123703-40-2Relevant articles and documents
Synthesis of perhydrofuro[2,3-b]furans from isopentenyl alcohol through carbonyl-ene and wacker-type reactions
Alonso, Francisco,Rodriguez-Fernandez, Mamen,Sanchez, Daniel,Yus, Miguel
, p. 6459 - 6469 (2011/12/05)
A range of 2-substituted perhydrofuro[2,3-b]furans have been synthesized in a stereoselective manner through a sequence involving the Lewis-acid catalyzed carbonyl-ene reaction of a protected isopentenyl alcohol with a variety of enophiles, deprotection of the corresponding monoprotected diols, and palladium-catalyzed intramolecular acetalization under Wacker-type reaction conditions. A new synthetic approach toward the synthesis of perhydrofuro[2,3-b]furans is described. The strategy is based on the carbonyl-ene reaction for a protected isopentenyl alcohol with several activated enophiles followed by deprotection and palladium-catalyzed intramolecular acetalization. Copyright
The stereoselective syntheses of substituted furo[2,3b]furans
Vader,Sengers,De Groot
, p. 2131 - 2142 (2007/10/02)
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