1240483-13-9 Usage
Description
(3aR,4R,5R,6aS)-5-((tert-butyldimethylsilyl)oxy)-4-((E)-3-oxo-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one is a complex organic compound characterized by a cyclopentane ring structure. It features a tert-butyldimethylsilyl group and an (E)-3-oxo-5-phenylpent-1-en-1-yl side chain, contributing to its unique chemical properties. With a molecular formula of C23H36O4Si, this compound is widely utilized in the fields of organic synthesis and medicinal chemistry.
Uses
Used in Organic Synthesis:
(3aR,4R,5R,6aS)-5-((tert-butyldimethylsilyl)oxy)-4-((E)-3-oxo-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one serves as a key intermediate in organic synthesis, particularly for the preparation of various pharmaceuticals and bioactive molecules. Its unique structure allows for versatile chemical modifications, facilitating the synthesis of a broad range of compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, this compound is employed as a building block for the development of novel therapeutic agents. Its cyclopentane ring and functional groups enable the design of molecules with specific biological activities, targeting various diseases and medical conditions.
Used in Pharmaceutical Industry:
(3aR,4R,5R,6aS)-5-((tert-butyldimethylsilyl)oxy)-4-((E)-3-oxo-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one is utilized in the pharmaceutical industry as a precursor for the synthesis of drug candidates. Its unique structural features make it a valuable component in the development of new medications with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 1240483-13-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,0,4,8 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1240483-13:
(9*1)+(8*2)+(7*4)+(6*0)+(5*4)+(4*8)+(3*3)+(2*1)+(1*3)=119
119 % 10 = 9
So 1240483-13-9 is a valid CAS Registry Number.
1240483-13-9Relevant articles and documents
Novel tail and head group prostamide probes
Finnegan, David F.,Shelnut, Erin L.,Nikas, Spyros P.,Chiang, Nan,Serhan, Charles N.,Makriyannis, Alexandros
supporting information, p. 1228 - 1231 (2015/04/13)
We report the design and synthesis of novel prostaglandin-ethanolamide (PGE2-EA) analogs containing head and tail group modifications to aid in the characterization of a putative prostamide receptor(s). Our synthetic approach utilizes Horner-Wadsworth-Emmons and Wittig reactions to construct the head and the tail moieties of the key PGE2 precursor, which leads to the final products through a peptide coupling, Swern oxidation and HF/pyridine assisted desilylation. The synthesized analogs were shown not to interact significantly with endocannabinoid proteins and recombinant EP1, EP3 and EP4 receptors and suggest a yet to be identified prostamide receptor as their site(s) of action.
