1242461-34-2

Basic information

• Product Name: (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl)cyclopetanecarboxaldehyde
• Synonyms: (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl)cyclopetanecarboxaldehyde
• CAS NO: 1242461-34-2
• Molecular Weight: 271.316
• Mol File: 1242461-34-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl)cyclopetanecarboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl)cyclopetanecarboxaldehyde(1242461-34-2)
• EPA Substance Registry System: (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl)cyclopetanecarboxaldehyde(1242461-34-2)

Safety Data

• Hazardous Substances Data: 1242461-34-2(Hazardous Substances Data)

Upstream product

• 941-69-5 N-phenyl-maleimide 
• 872-53-7 cyclopentanealdehyde 

Relevant articles and documents

N-Primary-amine tetrapeptide-catalyzed highly asymmetric Michael addition of aliphatic aldehydes to maleimides

The highly asymmetric Michael addition reaction between maleimides and aliphatic aldehydes catalyzed by low-loading β-turn tetrapeptides with excellent yields and enantioselectivities at room temperature was reported. α-Branched and α-unbranched aldehydes both are suitable nucleophiles. N-Aryl, alkyl and hydrogen maleimides all are well tolerated and led to high yields and enantioselectivities. The transformation can be enlarged to the gram scale without decrease in the yield and enantioselectivity. Furthermore, the succinimides were converted into γ-lactams and γ-lactones, showing good practicality of this work. Some reaction intermediates in the proposed reaction mechanism can be captured with the HR-MS method.

An asymmetric Michael addition of α,α-disubstituted aldehydes to maleimides leading to a one-pot enantioselective synthesis of lactones catalyzed by amino acids

A cheap and fast construction of both enantiomers of substituted succinimides is reported. α- or β-amino acids, such as β-phenylalanine and α-tert-butyl aspartate, were found to be efficient organocatalysts for the reaction between α,α-disubstituted aldeh

Michael addition of ketones and aldehydes to maleimides catalyzed by modularly designed organocatalysts

Modularly designed organocatalysts (MDOs) formed in situ from the self-assembly of primary α-amino acids and Cinchona alkaloid thioureas were found to be excellent catalysts for the stereoselective Michael addition of enolizable ketones and aldehydes to m