1244016-83-8

Basic information

• Product Name: methyl 4-(2-phenylethynyl)pyridine-2-carboxylate
• Synonyms: methyl 4-(2-phenylethynyl)pyridine-2-carboxylate
• CAS NO: 1244016-83-8
• Molecular Weight: 237.258
• Mol File: 1244016-83-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-phenylethynyl)pyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-phenylethynyl)pyridine-2-carboxylate(1244016-83-8)
• EPA Substance Registry System: methyl 4-(2-phenylethynyl)pyridine-2-carboxylate(1244016-83-8)

Safety Data

• Hazardous Substances Data: 1244016-83-8(Hazardous Substances Data)

Upstream product

• 29681-42-3 methyl 4-bromopyridine-2-carboxylate 
• 536-74-3 phenylacetylene 
• 5470-22-4 4-chloropicolinic acid 
• 98-98-6 2-Picolinic acid 
• 24484-93-3 4-Chloro-pyridine-2-carboxylic acid methyl ester 
• 405939-79-9 4-iodo-2-nicotinic acid 

Downstream Products

• 1244012-98-3 C₁₄H₁₀N₂O₂ 

Relevant articles and documents

Allosteric modulators of 5-hydroxytryptamine 2C receptor (5-HT2CR)

The disclosure is directed to compounds identified as allosteric modulators of 5-HT 2CR, as well as pharmaceutical compositions and methods using the same. Certain embodiments also include methods of identifying and methods of synthesizing the compounds. Optimization and development of allosteric 5-HT 2CR modulators that bind sites other than the primary ligand binding site generate novel, highly selective, and potent ligands of 5-HT2CR. Such molecules can be used as small molecule probes for the nervous system and as effective therapeutics for a variety of diseases.

HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS

The invention relates to chemical compounds of formula (IB): or a salt thereof. In some embodiments, the invention relates to inhibitors of UDP-3-0 — (R-S-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC). In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein and their use in the prevention and/or treatment of Gram- negative bacterial infections.