1244390-29-1

Basic information

• Product Name: (4R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)-3,4-dihydropyrano[3,2-c]chromen-5-(2H)one
• CAS NO: 1244390-29-1
• Molecular Weight: 362.305
• Mol File: 1244390-29-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)-3,4-dihydropyrano[3,2-c]chromen-5-(2H)one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)-3,4-dihydropyrano[3,2-c]chromen-5-(2H)one(1244390-29-1)
• EPA Substance Registry System: (4R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)-3,4-dihydropyrano[3,2-c]chromen-5-(2H)one(1244390-29-1)

Safety Data

• Hazardous Substances Data: 1244390-29-1(Hazardous Substances Data)

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 3108-32-5 (E)-1,1,1-trifluoro-4-phenyl-3-buten-2-one 

Relevant articles and documents

Highly enantioselective michael addition of cyclic 1,3-Dicarbonyl compounds to β,γ-Unsaturated α-Keto esters

A highly enantioselective Michael addition of cyclic 1,3-dicarbonyl compounds to β,γ-unsaturated α-keto esters catalyzed by amino acid-derived thiourea-tertiary-amine catalysts is presented. Using 5 mol% of a novel tyrosine-derived thiourea catalyst, a series of chiral coumarin derivatives were obtained in excellent yields (up to 99%) and with up to 96% ee under very mild conditions within a short reaction time.