124525-54-8

Basic information

• Product Name: 2-methyl-3-(3-nitrophenyl)propenoic acid
• Synonyms: 2-methyl-3-(3-nitrophenyl)propenoic acid
• CAS NO: 124525-54-8
• Molecular Weight: 207.186
• Mol File: 124525-54-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-methyl-3-(3-nitrophenyl)propenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-3-(3-nitrophenyl)propenoic acid(124525-54-8)
• EPA Substance Registry System: 2-methyl-3-(3-nitrophenyl)propenoic acid(124525-54-8)

Safety Data

• Hazardous Substances Data: 124525-54-8(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 516-05-2 methyl-propanedioic acid 
• 99-61-6 3-nitro-benzaldehyde 
• 79-41-4 poly(methacrylic acid) 
• 2028-76-4 3-nitrophenyldiazonium chloride 
• 802294-64-0 propionic acid 
• 99-09-2 3-nitro-aniline 

Downstream Products

• 119870-76-7 (E)-ethyl 2-methyl-3-(3-nitrophenyl)acrylate 
• 39157-06-7 α-methyl-m-nitrocinnamic acid chloride 
• 1261078-82-3 (E)-2-methyl-3-(3-(quinoxalin-3-ylamino)phenyl)acrylic acid 
• 216576-08-8 (E)-ethyl 3-(3-aminophenyl)-2-methylacrylate 
• 39896-32-7 1-(3-nitrophenyl)propan-2-one 
• 336181-47-6 2-[1-methyl-2-(3-nitro-phenyl)-vinyl]-1H-benzoimidazole 
• 93130-69-9 phenyl α-methyl-m-guanidinophenylpropionate methanesulfonate 
• 93130-45-1 phenyl α-methyl-m-guanidinocinnamate methanesulfonate 
• 93130-87-1 phenyl α-methyl-m-aminocinnamate methanesulfonate 
• 69693-97-6 phenyl α-methyl-m-nitrocinnamate 
• 41201-56-3 (+/-)-3-(3-amino-phenyl)-2-methyl-propionic acid 
• 103205-22-7 3t-(3-amino-phenyl)-2-methyl-acrylic acid 
• 90917-62-7 3-(3-amino-2,4,6-triiodo-phenyl)-2-methyl-propionic acid 

Relevant articles and documents

Sodium tetraborate/benzyltriethylammonium chloride-mediated synthesis of substituted cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids

A simple, efficient, and cost-effective method has been developed for the synthesis of some cinnamic acid derivatives in moderate to high yields (63-86%) by a one-pot condensation reaction of benzaldehyde and aliphatic carboxylic acids in the presence of sodium tetraborate and benzyltriethylammonium chloride, and N-methyl-pyrrolidinone as solvent. The reaction requires high temperatures (reflux at 180-190°C) and strong basic conditions, which have been generated by pyridine and 4-dimethylaminopyridine added to the reaction medium.

A novel direct boron-mediated synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids

Cinnamic acids have been prepared in 64-85% yields by a new direct synthesis from aromatic aldehydes and aliphatic carboxylic acids in the presence of anhydrous sodium tetraborate and lithium chloride, bases as pyridine (Py) and 4-dimethylaminopyridine (DMAP), and N-methyl-2-pyrolidinone (NMP) as solvent, at reflux (180-190°C), for 8-12 hours. Without sodium tetraborate-lithium chloride this reaction is not possible.

Carboxamide compounds as SRS-A antagonists

The compounds of the invention are certain new propenamides and 2-butenamides having a (carboxyalkanamido)phenyl or a (carboxyalkenamido)phenyl group at the 3-position, and certain esters thereof, and certain cyclopropanecarboxamide compounds having a (ca