1245276-87-2

Basic information

• Product Name: (Z)-2,6-dibromo-4-{(6-fluoro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ylidene)methyl}phenyl acetate
• Synonyms: (Z)-2,6-dibromo-4-{(6-fluoro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ylidene)methyl}phenyl acetate
• CAS NO: 1245276-87-2
• Molecular Weight: 471.077
• Mol File: 1245276-87-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2,6-dibromo-4-{(6-fluoro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ylidene)methyl}phenyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2,6-dibromo-4-{(6-fluoro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ylidene)methyl}phenyl acetate(1245276-87-2)
• EPA Substance Registry System: (Z)-2,6-dibromo-4-{(6-fluoro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ylidene)methyl}phenyl acetate(1245276-87-2)

Safety Data

• Hazardous Substances Data: 1245276-87-2(Hazardous Substances Data)

Upstream product

• 2973-77-5 3,5-dibromo-4-hydroxybenzaldehyde 
• 108-24-7 acetic anhydride 
• 398-63-0 6-fluoro-2H-1,4-benzoxazin-3(4H)-one 

Downstream Products

• 1245276-99-6 (Z)-2-(3,5-dibromo-4-hydroxybenzylidene)-6-fluoro-2H-benzo[b][1,4]oxazin-3-(4H)-one 

Relevant articles and documents

Synthesis of 2-benzylidene and 2-hetarylmethyl derivatives of 2H-1,4-benzoxazin-3-(4H)-ones as neuroprotecting agents

A wide variety of the title compounds were synthesized by conventional and microwave methods in which the main step is a condensation of an aldehyde with a 1,4-benzoxazin-3-(4H)-one. In all cases, the Z diasteromers were the major products. Of particular importance is the synthesis of novel 2-(3,5-dibromo-4-hydroxy) and 2-(4-acetoxy-3,5-dibromobenzylidene derivatives of 2H-1,4-benzoxazin-3-(4H)-ones, four of which were shown in a previous publication to exhibit potent neuroprotecting properties. The yields of titled compounds ranged from 25 to 83%. Copyright Taylor & Francis Group, LLC.