1245647-80-6 Usage
General Description
3-(2,3-dihydro-6-hydroxybenzo[b][1,4]dioxin-7-yl)indolin-2-one, also known as CEP-1347, is a chemical compound with potential pharmaceutical applications. It is a synthetic, small molecule inhibitor of mixed-lineage kinase (MLK) which has been studied for its potential use in treating neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. CEP-1347 has been shown to have neuroprotective effects in preclinical models of neurodegenerative diseases by inhibiting the activation of MLK and downstream signaling pathways involved in neuronal cell death. Additionally, it has been investigated in clinical trials for its potential use in treating neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1245647-80-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,6,4 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1245647-80:
(9*1)+(8*2)+(7*4)+(6*5)+(5*6)+(4*4)+(3*7)+(2*8)+(1*0)=166
166 % 10 = 6
So 1245647-80-6 is a valid CAS Registry Number.
1245647-80-6Relevant articles and documents
SYNTHETIC METHODS FOR SPIRO-OXINDOLE COMPOUNDS
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Page/Page column 12, (2011/04/25)
This invention is directed to methods of preparing certain spiro-oxindole derivatives, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
