125111-05-9Relevant articles and documents
Fluorouracil derivatives with serum protein binding potencies
Yamashita,Suda,Masada,Nadai,Sumi
, p. 2861 - 2863 (2007/10/02)
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125111-05-9
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Basic information
- Product Name: 1-(2,4-Dichlorobenzyl)-5-fluorouracil
- Synonyms: 1-(2,4-Dichlorobenzyl)-5-fluorouracil;5-FUDCB
- CAS NO:125111-05-9
- Molecular Formula: C11H7Cl2FN2O2
- Molecular Weight: 289.09
- EINECS: N/A
- Product Categories: N/A
- Mol File: 125111-05-9.mol
- Article Data: 1
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(2,4-Dichlorobenzyl)-5-fluorouracil(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(2,4-Dichlorobenzyl)-5-fluorouracil(125111-05-9)
- EPA Substance Registry System: 1-(2,4-Dichlorobenzyl)-5-fluorouracil(125111-05-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 125111-05-9(Hazardous Substances Data)
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125111-05-9 Usage
Description
1-(2,4-Dichlorobenzyl)-5-fluorouracil is a chemical compound derived from 5-fluorouracil, which is a medication used for the treatment of certain types of cancer. 1-(2,4-Dichlorobenzyl)-5-fluorouracil features a 1-(2,4-Dichlorobenzyl) group that significantly enhances its antitumor activity, making it a potent cytostatic agent. It is recognized for its ability to inhibit DNA replication and induce cell death in rapidly dividing cancer cells, thus offering a promising therapeutic approach for cancer treatment.Uses
Used in Anticancer Applications:1-(2,4-Dichlorobenzyl)-5-fluorouracil is used as an anticancer agent for its enhanced ability to inhibit DNA replication and cause cell death in cancer cells. This makes it particularly effective in the treatment of various solid tumors, including breast, colon, and stomach cancers. Its potent cytostatic properties contribute to its ongoing research and exploration in combination therapies and targeted treatments for a wide range of cancer types.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(2,4-Dichlorobenzyl)-5-fluorouracil is used as a key compound in the development of new cancer treatments. Its enhanced antitumor activity compared to the parent compound, 5-fluorouracil, makes it a valuable asset in the creation of more effective medications for cancer patients. The ongoing research into its potential in combination therapies and targeted treatments highlights its importance in advancing cancer treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 125111-05-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,1,1 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.Calculate Digit Verification of CAS Registry Number 125111-05:
(8*1)+(7*2)+(6*5)+(5*1)+(4*1)+(3*1)+(2*0)+(1*5)=69
69 % 10 = 9
So 125111-05-9 is a valid CAS Registry Number.
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1-(2,4-Dichlorobenzyl)-5-fluorouracil
