125577-52-8Relevant articles and documents
4,5-Dihydroxyimidazolidin-2-ones in a-ureidoalkylation of N-carboxy-, N-hydroxy-, and N-aminoalkylureas 2. α-Ureidoalkylation of N-(hydroxyalkyl)ureas
Kravchenko,Sigachev,Belyakov,Ilyin,Lyssenko,Davankov,Lebedev,Makhova,Tartakovsky
experimental part, p. 1264 - 1269 (2010/10/04)
sThe a-ureidoalkylation of N-(hydroxyalkyl)ureas (ureido alcohols) with 1,3-H3-and 1,3-Me2-4,5-dihydroxyimidazolidin-2-ones was systematically studied. The yields of glycolurils decrease both in going from 1,3-H2-to 1,3-Me2-4,5-dihydroxyimidazolidin-2-one and with increasing length (or with branching) of the hydroxyalkyl chain in ureido alcohols. The optimal reaction time for ureido alcohols is 1 h. The X-ray diffraction study showed that 2-(2-hydroxy-1,1-dimethylethyl)glycoluril crystallizes as a conglomerate. The enantiomeric analysis of 2-(2-hydroxyethyl)glycoluril was carried out by chiral-phase HPLC. ; 2009 Springer Science+Business Media, Inc.
