125592-99-6

Basic information

• Product Name: 1-(methoxycarbonyl)-2-(4-bromophenyl)-1,2,3,4-tetrahydropyridine
• Synonyms: 1-(methoxycarbonyl)-2-(4-bromophenyl)-1,2,3,4-tetrahydropyridine
• CAS NO: 125592-99-6
• Molecular Weight: 296.164
• Mol File: 125592-99-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(methoxycarbonyl)-2-(4-bromophenyl)-1,2,3,4-tetrahydropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(methoxycarbonyl)-2-(4-bromophenyl)-1,2,3,4-tetrahydropyridine(125592-99-6)
• EPA Substance Registry System: 1-(methoxycarbonyl)-2-(4-bromophenyl)-1,2,3,4-tetrahydropyridine(125592-99-6)

Safety Data

• Hazardous Substances Data: 125592-99-6(Hazardous Substances Data)

Upstream product

• 56475-87-7 3,4-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 589-87-7 1,4-bromoiodobenzene 

Relevant articles and documents

Regioselective Palladium-Catalyzed Tandem α-Arylation/Isomerization of Cyclic Enamides

Palladium-catalyzed reactions of aryl iodides with the cyclic enamides 1-(methoxycarbonyl)-1,4,5,6-tetrahydropyridine (1), 1-formyl-1,4,5,6-tetrahydropyridine (2), and 1-formyl-2-pyrroline (3) result in regioselective α-arylation, with concomitant isomerization of the double bond into conjugation with the nitrogen atom.The new enamides 1-(methoxycarbonyl)-2-aryl-1,2,3,4-tetrahydropyridines (4), 1-formyl-2-aryl-1,2,3,4-tetrahydropyridines (5), and 1-formyl-5-phenyl-2-pyrroline (6a) were isolated in various yields.The migration of the double bond is affected (a) by an amino group in the ortho position of the aryl iodide; (b) by the presence of silver salts; and (c) partly by a 4-methyl group in the tetrahydropyridine ring.In these cases the allylic compounds 2-aryl-1,2,5,6-tetrahydropyridines (10a,b and 13) are formed.