1257985-11-7Relevant articles and documents
Direct alkynylation of thiophenes: Cooperative activation of TIPS-EBX with gold and Bronsted acids
Brand, Jonathan P.,Waser, Jerome
supporting information; experimental part, p. 7304 - 7307 (2010/11/05)
United we stand! Cooperative activation of the hypervalent-iodine reagent TIPS-EBX with a gold catalyst and a Bronsted acid allowed the first direct ethynylation of thiophenes at room temperature (see scheme; TFA = trifluoroacetic acid). The obtained ethynylthiophenes are important building blocks for organic dyes and electronic materials.