1262121-47-0

Basic information

• Product Name: N-[2-(3-hydroxyphenyl)-2-oxo-ethyl]-N-methyl-acetamide
• Synonyms: N-[2-(3-hydroxyphenyl)-2-oxo-ethyl]-N-methyl-acetamide
• CAS NO: 1262121-47-0
• Molecular Weight: 207.229
• Mol File: 1262121-47-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(3-hydroxyphenyl)-2-oxo-ethyl]-N-methyl-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3-hydroxyphenyl)-2-oxo-ethyl]-N-methyl-acetamide(1262121-47-0)
• EPA Substance Registry System: N-[2-(3-hydroxyphenyl)-2-oxo-ethyl]-N-methyl-acetamide(1262121-47-0)

Safety Data

• Hazardous Substances Data: 1262121-47-0(Hazardous Substances Data)

Upstream product

• 679395-42-7 O-acetyl,N-acetylphenylephrone 

Downstream Products

• 1477-63-0 Phenylephrine 
• 1262121-49-2 C₁₁H₁₅NO₃ 
• 58952-80-0 C₁₁H₁₅NO₃ 
• 69728-91-2 N-acetyl-1-(3-hydroxyphenyl)-2-methylaminoethanol 

Relevant articles and documents

A feasibility study on the synthesis of phenylephrine via ruthenium-catalyzed homogeneous asymmetric hydrogenation

We report a feasibility study on a new route to (R)-phenylephrine, based on the ruthenium-catalyzed asymmetric hydrogenation of an aminoketone precursor. The direct and fast asymmetric reduction of aminoketones or their hydrochloride salts is achievable at low catalyst loadings (molar substrate to catalyst ratio, S/C, >25,000/1, TOF up to 25,000 h-1) with high enantioselectivity (>95% ee), without the need for N-protection nor isolation of the free base prior to reaction.