126257-07-6 Usage
Description
H-P-AMINO-D-PHE-OH HCL, also known as 4-Amino-D-phenylalanine Hydrochloride, is an organic compound that serves as a crucial reagent in the synthesis of various pharmaceuticals. It is a derivative of amino acids, specifically D-phenylalanine, with a hydrochloride salt form that enhances its solubility and stability.
Used in Pharmaceutical Industry:
H-P-AMINO-D-PHE-OH HCL is used as a reagent for the synthesis of D-Melphalan (M216915), an isomer of Melphalan (M216900). D-Melphalan is an antineoplastic agent, which means it has the ability to inhibit the growth and proliferation of cancer cells. This makes H-P-AMINO-D-PHE-OH HCL an essential component in the development of cancer treatments.
In the synthesis of D-Melphalan, H-P-AMINO-D-PHE-OH HCL plays a critical role as it contributes to the formation of the final product, which possesses antineoplastic properties. This application highlights the importance of H-P-AMINO-D-PHE-OH HCL in advancing cancer research and therapeutics, ultimately aiming to improve patient outcomes and survival rates.
Check Digit Verification of cas no
The CAS Registry Mumber 126257-07-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,2,5 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 126257-07:
(8*1)+(7*2)+(6*6)+(5*2)+(4*5)+(3*7)+(2*0)+(1*7)=116
116 % 10 = 6
So 126257-07-6 is a valid CAS Registry Number.
126257-07-6Relevant articles and documents
Biosynthesis of the Antibiotic Obafluorin from D-Glucose and p-Aminophenylalanine in Pseudomonas fluorescens
Herbert, Richard B.,Knaggs, Andrew R.
, p. 103 - 108 (2007/10/02)
The separate units which are used to construct the antibiotic obafluorin 1 in Pseudomonas fluorescens are defined by the results of D-glucose incorporation.A key intermediate in the biosynthesis of 1 is established to be L-p-aminophenylalanine 8; L-phenylanaline and L-p-nitrophenylalanine are very poor precursors.Results similar to those for obafluorin are obtained for p-nitrophenylacetic acid 20 which along with derivative 4 and 2-(4-nitrophenyl)ethanol 21 are identified as new metabolites of P. fluorescens.Deuteriated samples of 20, 22 and 23 are notprecursors for obafluorin 1. -p-aminophenylalanine 18 is incorporated into 1 with complete loss of deuterium from C-2 but retention of the deuterium present in both diastereotopic positions on C-3.
