1263101-72-9

Basic information

• Product Name: C₈H₁₅ClO₃S
• Synonyms: C₈H₁₅ClO₃S
• CAS NO: 1263101-72-9
• Molecular Weight: 226.724
• Mol File: 1263101-72-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈H₁₅ClO₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H₁₅ClO₃S(1263101-72-9)
• EPA Substance Registry System: C₈H₁₅ClO₃S(1263101-72-9)

Safety Data

• Hazardous Substances Data: 1263101-72-9(Hazardous Substances Data)

Upstream product

• 1256080-00-8 methylthiomethyl 2-ethoxy-2-methylpropanoate 
• 151598-88-8 ethyl 2-ethoxy-2-methylpropanoate 
• 15001-71-5 2-ethoxy-2-methyl-propanoic acid 
• 76474-10-7 2-ethoxyisobutyronitrile 

Relevant articles and documents

Development of a practical and efficient synthesis of chloromethyl 2-ethoxy-2-methylpropanoate

An efficient synthesis of chloromethyl 2-ethoxy-2-methylpropanoate from 2-bromoisobutyric acid is reported. Four developments were key to this route: (i) a mild, base-mediated ethanolysis of a tertiary alkyl bromide, (ii) a sodium bisulfite purge of 2-methylacrylic acid, (iii) preparation of a thiomethyl ester via a formal Pummerer process with DMSO, and (iv) improved conversion of a thiomethyl ester to a chloromethyl ester through suppression of a competing chlorination pathway.