126521-57-1

Basic information

• Product Name: 1-(4-hydroxyphenyl)pent-1-en-3-one
• Synonyms: 1-(4-hydroxyphenyl)pent-1-en-3-one
• CAS NO: 126521-57-1
• Molecular Weight: 176.215
• Mol File: 126521-57-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-hydroxyphenyl)pent-1-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-hydroxyphenyl)pent-1-en-3-one(126521-57-1)
• EPA Substance Registry System: 1-(4-hydroxyphenyl)pent-1-en-3-one(126521-57-1)

Safety Data

• Hazardous Substances Data: 126521-57-1(Hazardous Substances Data)

Upstream product

• 4397-53-9 p-benzyloxybenzaldehyde 
• 30802-00-7 4-coumaroyl-coenzyme A 
• 1264-45-5 (2RS)-methylmalonyl-CoA 
• 123-08-0 4-hydroxy-benzaldehyde 
• 78-93-3 butanone 

Downstream Products

• 93648-82-9 4-(5-ethyl-2-phenyl-3,4-dihydro-2H-pyrazol-3-yl)-phenol 
• 91970-25-1 1-(4-hydroxyphenyl)pentan-3-one 

Relevant articles and documents

Enzymatic formation of an unnatural C6-C5 aromatic polyketide by plant type III polyketide synthases

(graph presented) Substrate specificities of plant polyketide synthases (PKSs) were investigated using analogues of malonyl-CoA, the extension unit of the polyketide chain elongation reactions. When incubated with methylmalonyl-CoA and 4-coumaroyl-CoA, plant PKSs (chalcone synthase from Scutellaria baicalensis, stilbene synthase from Arachis hypogaea, and benzalacetone synthase from Rheum palmatum) afforded an unnatural C6-C5 aromatic polyketide, 1-(4-hydroxyphenyl)pent-1-en-3-one, formed by one-step decarboxylative condensation of the two substrates. In contrast, succinyl-CoA was not accepted as a substrate by the enzymes.

Propanamine derivatives

Substituted propanamines having anticoagulant or antifungal activity are disclosed. Also disclosed are methods of use involving the substituted propanamines as well as pharmaceutical compositions containing them.