1265223-32-2

Basic information

• Product Name: 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate
• Synonyms: 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate
• CAS NO: 1265223-32-2
• Molecular Weight: 354.316
• Mol File: 1265223-32-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate(1265223-32-2)
• EPA Substance Registry System: 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate(1265223-32-2)

Safety Data

• Hazardous Substances Data: 1265223-32-2(Hazardous Substances Data)

Upstream product

• 6665-78-7 5,7-di-O-acetyl chrysin 
• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 

Downstream Products

• 1265223-39-9 3-hydroxy-4-oxo-2-phenyl-4H-chromene-5,7-diyl diacetate 

Relevant articles and documents

APP SPECIFIC BACE INHIBITORS (ASBIs) AND USES THEREOF

In certain embodiments APP-specific BACE inhibitors (ASBIs) are provided as well as uses thereof. In certain embodiments methods of preventing or delaying the onset of a pre-Alzheimer's condition and/or cognitive dysfunction, and/or ameliorating one or more symptoms of a pre-Alzheimer's condition and/or cognitive dysfunction, or preventing or delaying the progression of a pre-Alzheimer's condition or cognitive dysfunction to Alzheimer's disease are provided where the method involves administering to a subject in need thereof an APP specific BACE inhibitor (ASBI) in an amount sufficient to prevent or delay the onset of a pre-Alzheimer's cognitive dysfunction, and/or to ameliorate one or more symptoms of a pre-Alzheimer's cognitive dysfunction, and/or to prevent or delay the progression of a pre-Alzheimer's cognitive dysfunction to Alzheimer's disease. In certain embodiments the ASBI is a flavonoid (e.g. galangin) or flavonoid progrug (e.g., galangin prodrug).