1268635-18-2

Basic information

• Product Name: (2R,3R)-dimethyl-[2-methyl-3-(3-amino-phenyl)-pentyl]-amine
• Synonyms: (2R,3R)-dimethyl-[2-methyl-3-(3-amino-phenyl)-pentyl]-amine
• CAS NO: 1268635-18-2
• Molecular Weight: 220.358
• Mol File: 1268635-18-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-dimethyl-[2-methyl-3-(3-amino-phenyl)-pentyl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-dimethyl-[2-methyl-3-(3-amino-phenyl)-pentyl]-amine(1268635-18-2)
• EPA Substance Registry System: (2R,3R)-dimethyl-[2-methyl-3-(3-amino-phenyl)-pentyl]-amine(1268635-18-2)

Safety Data

• Hazardous Substances Data: 1268635-18-2(Hazardous Substances Data)

Upstream product

• 17408-16-1 3'-nitropropiophenone 
• 1309956-63-5 3-dimethylamino-2-methyl-1-(m-nitrophenyl)-1-propanone 
• 1309956-64-6 (S)-3-(dimethylamino)-2-methyl-1-(3-nitrophenyl)-propan-1-one (2R,3R)-O,O'-dibenzoyltartrate 
• 1309956-65-7 (S)-3-(dimethylamino)-2-methyl-1-(3-aminophenyl)-propan-1-one 
• 1309956-66-8 (2S,3R)-3-(3-amino-phenyl)-1-(dimethylamino)-2-methyl-pentan-3-ol 
• 1309956-67-9 C₁₈H₂₂F₆N₂O₃ 
• 1309956-68-0 C₁₆H₂₃F₃N₂O 
• 53013-01-7 3-(dimethylamino)-2-methyl-1-(3-nitro-phenyl)-propan-1-one 

Downstream Products

• 175591-09-0 tapentadol hydrochloride 

Relevant articles and documents

NEW PROCESS FOR THE PREPARATION OF TAPENTADOL AND INTERMEDIATES THEREOF

The present invention refers to a new process for the synthesis of tapentadol comprising the quantitative resolution of the racemic mixture (V) to obtain the stereoisomer of (S)-3-(dimethylamino)-2-methyl-l-(3-nitrophenyl)-propan-l-one (VII) according to