127236-74-2

Basic information

• Product Name: (1R,2S,5R)-(-)-menthyl diazoacetoacetate
• Synonyms: (1R,2S,5R)-(-)-menthyl diazoacetoacetate
• CAS NO: 127236-74-2
• Molecular Weight: 266.34
• Mol File: 127236-74-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-(-)-menthyl diazoacetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-(-)-menthyl diazoacetoacetate(127236-74-2)
• EPA Substance Registry System: (1R,2S,5R)-(-)-menthyl diazoacetoacetate(127236-74-2)

Safety Data

• Hazardous Substances Data: 127236-74-2(Hazardous Substances Data)

Upstream product

• 2216-51-5 (-)-menthol 
• 59557-05-0 (L)-menthyl 3-oxobutyrate 

Downstream Products

• 63254-50-2 L-menthyl diazoacetate 
• 1031781-61-9 C₁₅H₂₆O₄ 
• 213826-10-9 (E)-4-((1S,2R,3S,6R)-3-Isopropyl-2-methoxymethoxy-6-methyl-cyclohexyl)-2-methyl-but-2-enoic acid ethyl ester 
• 213826-08-5 (1R,2S,3R,6S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-6-isopropyl-3-methyl-cyclohexanol 
• 213826-12-1 4-((1S,2R,3S,6R)-3-Isopropyl-2-methoxymethoxy-6-methyl-cyclohexyl)-butan-2-one 
• 1026873-37-9 2-((1S,2R,3S,6R)-3-Isopropyl-2-methoxymethoxy-6-methyl-cyclohexyl)-ethanol 
• 213826-09-6 ((1S,2R,3S,6R)-3-Isopropyl-2-methoxymethoxy-6-methyl-cyclohexyl)-acetaldehyde 
• 213826-06-3 (1S,2S,3R,6S)-2-(2-Hydroxy-ethyl)-6-isopropyl-3-methyl-cyclohexanol 

Relevant articles and documents

Addition of Diazo Compounds ipso -C-H Bond to Carbon Disulfide: Synthesis of 1,2,3-Thiadiazoles under Mild Conditions

We describe here an operationally simple and straightforward synthesis method for a series of diverse 4,5-disubstituted 1,2,3-thiadiazoles via the nucleophilic addition of α-diazo carbonyl compounds to carbon disulfide. This method features using abundant and inexpensive carbon disulfide under mild reaction conditions.

Enantioselective Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds

Enantioselective catalytic methods allowing the addition of both a nucleophile and an electrophile onto diazo compounds give a fast access into important building blocks. Herein, we report the highly enantioselective oxyalkynylation of diazo compounds usi

Catalyzed addition of diazoacetoacetates to imines: Synthesis of highly functionalized aziridines

The addition of diazoacetoacetates to aromatic imines derived from p-methoxyaniline is achieved using dirhodium tetraacetate as the catalyst. Highly functionalized aziridines are obtained in good yield and with excellent stereoselectivity. 2-Diazo-1,3-diketones also provide good yields of aziridines, but dimethyl diazomalonate is inactive in the transformation. The diazoacetoacetates of chiral alcohols are also examined in the reaction and moderate diastereoselectivity is achieved with (R)-pantolactone-derived diazoacetoacetate. A reaction mechanism through metal-carbene and azomethine ylide is proposed.