127246-04-2

Basic information

• Product Name: 3-benzyl-2,3-dihydro-2-methoxycarbonyl-1-methyl-3-indazolecarbonitrile
• Synonyms: 3-benzyl-2,3-dihydro-2-methoxycarbonyl-1-methyl-3-indazolecarbonitrile
• CAS NO: 127246-04-2
• Molecular Weight: 307.352
• Mol File: 127246-04-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyl-2,3-dihydro-2-methoxycarbonyl-1-methyl-3-indazolecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2,3-dihydro-2-methoxycarbonyl-1-methyl-3-indazolecarbonitrile(127246-04-2)
• EPA Substance Registry System: 3-benzyl-2,3-dihydro-2-methoxycarbonyl-1-methyl-3-indazolecarbonitrile(127246-04-2)

Safety Data

• Hazardous Substances Data: 127246-04-2(Hazardous Substances Data)

Upstream product

• 13436-48-1 1-methyl-1H-indazole 
• 127246-00-8 2,3-dihydro-2-methoxycarbonyl-1-methyl-3-indazolecarbonitrile 

Relevant articles and documents

Reissert Compound Formation with Fused Five-Membered Ring Heterocycles

Reissert compounds have been prepared in high yield from benzothiazole by use of trimethylsilyl cyanide as source of cyanide in a single phase system.Analogues have been made from benzoxazole, indazole and 1-methylindazole but the method was unsuccessful with 1,2-benzisoxazole and pyrazole.Conjugate base alkylation followed by removal of the Reissert grouping provides a route to 2-alkylbenzothiazoles and -benzoxazoles, and 3-alkylated indazoles.Efficient access to pyridobenzothiazole and benzothiazoloisoquinoline derivatives results from appropriate intramolecular cyclisations.A crystal structure determination of 3-benzoyl-2,3-dihydro-2-benzothiazolecarbonitrile is reported.