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127343-08-2

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127343-08-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 127343-08-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,3,4 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127343-08:
(8*1)+(7*2)+(6*7)+(5*3)+(4*4)+(3*3)+(2*0)+(1*8)=112
112 % 10 = 2
So 127343-08-2 is a valid CAS Registry Number.

127343-08-2Downstream Products

127343-08-2Relevant articles and documents

3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors. 7. Modification of the Hexahydronaphthalene Moiety of Simvastanin: 5-Oxygenated and 5-Oxa Derivatives

Duggan, Mark E.,Alberts, Alfred W.,Bostedor, Rick,Chao, Yu-sheng,Germershausen, John I.,et al.

, p. 2489 - 2495 (2007/10/02)

Modification of the hexahydronaphthalene ring 5-position in simvastatin 2a via oxygenation and oxa replacement afforded two series of derivatives which were evaluated in vitro for inhibition of 3-hydroxy-3-methylglutaryl-coenzyme.A reductase and acutely i

5-oxygenated HMG-CoA reductase inhibitors

-

, (2008/06/13)

Novel HMG-CoA reductase inhibitors are useful as antihypercholesterolemic agents and are represented by structural formulae (I) or (II): STR1 wherein position 5 of the polyhydronaphthyl ring is singly or doubly bonded to oxygen or incorporated into a C3-7 carbocyclic ring.

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