127568-50-7

Basic information

• Product Name: N-benzhydrylfuran-2-carboxamide
• Synonyms: N-benzhydrylfuran-2-carboxamide
• CAS NO: 127568-50-7
• Molecular Weight: 277.323
• Mol File: 127568-50-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-benzhydrylfuran-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzhydrylfuran-2-carboxamide(127568-50-7)
• EPA Substance Registry System: N-benzhydrylfuran-2-carboxamide(127568-50-7)

Safety Data

• Hazardous Substances Data: 127568-50-7(Hazardous Substances Data)

Upstream product

• 88-14-2 2-furanoic acid 
• 91-00-9 Benzhydrylamine 
• 609-38-1 furan-2-carboxylic acid amide 
• 101-81-5 Diphenylmethane 
• 527-69-5 2-furancarbonyl chloride 

Downstream Products

• 54220-18-7 N-furfurylidene-1,1-diphenylmethylamine 

Relevant articles and documents

Method for synthesizing amide compound by taking nitrile and diaryl methane as raw materials

The invention discloses a method for synthesizing an amide compound by taking nitrile and diaryl methane as raw materials, the method comprises the following steps: taking diaryl methane as a reaction raw material, nitrile as a raw material and a solvent, 2, 3-dichloro-5, 6-dinitrile group-1, 4-benzoquinone (DDQ) and tert-butyl nitrite (TBN) as catalysts, acid as an auxiliary agent and oxygen as an oxidizing agent, reacting under the conditions of normal temperature, normal pressure and blue light irradiation, and after the reaction is finished, carrying out separation treatment to obtain the amide compound. According to the method, the problem of metal residues in the product can be solved, oxygen is used as a terminal oxidizing agent, the method is environmentally friendly, and energy can be saved.

Synthesis and antifungal activity evaluation of new heterocycle containing amide derivatives

A series of heterocycle containing amide derivatives (1-28) were synthesised by the combination of acyl chlorides (1a, 2a) and heterocyclic/homocyclic ring containing amines, and their in vitro antifungal activity was evaluated against five plant pathogenic fungi, namely Gibberella zeae, Helminthosporium maydis, Rhizoctonia solani, Botrytis cinerea and Sclerotinia sclerotiorum. Results of antifungal activity analysis indicated that some of the products showed good to excellent antifungal activity, as compound 2 showed excellent activity against G. zeae and R. solani and potent activity against H. maydi, B. cinerea and S. sclerotiorum, and compounds 1, 8 and 10 also displayed excellent antifungal potential against H. maydi, B. cinerea and S. sclerotiorum and good activity against R. solani when compared with the standard carbendazim.

Synthesis and anticonvulsant activity of benzhydrylamines

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