1277176-12-1

Basic information

• Product Name: 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde
• Synonyms: 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde
• CAS NO: 1277176-12-1
• Molecular Weight: 278.046
• Mol File: 1277176-12-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde(1277176-12-1)
• EPA Substance Registry System: 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde(1277176-12-1)

Safety Data

• Hazardous Substances Data: 1277176-12-1(Hazardous Substances Data)

Upstream product

• 7149-92-0 2,4-dimethoxy-3-methylbenzaldehyde 

Downstream Products

• 1277176-10-9 C₁₉H₂₂O₃ 
• 549-23-5 7-epi-sclerotiorin 
• 521-90-4 sclerotioramine 
• 915789-22-9 6-ethynyl-2,4-dihydroxy-3-methylbenzaldehyde 

Relevant articles and documents

Synthesis of the azaphilones (+)-sclerotiorin and (+)-8- O -methylsclerotiorinamine utilizing (+)-sparteine surrogates in copper-mediated oxidative dearomatization

Enantioselective syntheses of the azaphilone natural products (+)-sclerotiorin and (+)-8-O-methylsclerotiorinamine that possess the natural R-configuration at the quaternary center are reported. The syntheses were accomplished using copper-mediated asymmetric dearomatization employing bis-i-oxo copper complexes prepared from readily available (+)-sparteine surrogates. Of note, site-selective O-methylation of a vinylogous pyridone was used to access the isoquinolin-6(7H)-one core of (+)-8-O- methylsclerotiorinamine.