12778-32-4

Basic information

• Product Name: BETA-BUNGAROTOXIN
• Synonyms: ERABUTOXIN B;BETA-BUNGAROTOXIN;BETA-BUTX;BUNGARUS MULTICINCTUS TOXIN, BETA;beta-bungarotoxi;B-BUNGAROTOXIN (BUTX) (BUNGARUS MULTICIN CTU;β-Bungarotoxin from Bungarus multicinctus (Formosan Banded Krait);Erabutoxin B from Laticauda semifasciata (Sea Snake)
• CAS NO: 12778-32-4
• Molecular Formula: C50H70O14
• Molecular Weight: 895.0824
• EINECS: 235-821-5
• Product Categories: OthersCell Signaling and Neuroscience;Cholinergics;Neurotransmitters;Snake;Toxins and Venoms
• Mol File: 12778-32-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: BETA-BUNGAROTOXIN(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-BUNGAROTOXIN(12778-32-4)
• EPA Substance Registry System: BETA-BUNGAROTOXIN(12778-32-4)

Safety Data

• WGK Germany: 3
• RTECS: EI6201000
• Hazardous Substances Data: 12778-32-4(Hazardous Substances Data)

Usage

General Description

BETA-BUNGAROTOXIN is a neurotoxin found in the venom of the Many-banded krait (Bungarus multicinctus), a highly venomous snake native to East and Southeast Asia. It is a postsynaptic neurotoxin that specifically targets and blocks the nicotinic acetylcholine receptor, leading to paralysis and respiratory failure. BETA-BUNGAROTOXIN is known to also affect the central nervous system, leading to symptoms such as double vision, difficulty swallowing, and muscle weakness. The toxin has been studied for its potential therapeutic applications, particularly in treating neurological disorders such as myasthenia gravis, a condition characterized by muscle weakness and fatigue. Additionally, the structure and function of BETA-BUNGAROTOXIN have been of interest to researchers in the field of pharmacology and neurobiology.