1279818-81-3

Basic information

• Product Name: ethyl 2-(4-nitrophenyl)oxazole-4-carboxylate
• Synonyms: ethyl 2-(4-nitrophenyl)oxazole-4-carboxylate
• CAS NO: 1279818-81-3
• Molecular Weight: 262.222
• Mol File: 1279818-81-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-nitrophenyl)oxazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-nitrophenyl)oxazole-4-carboxylate(1279818-81-3)
• EPA Substance Registry System: ethyl 2-(4-nitrophenyl)oxazole-4-carboxylate(1279818-81-3)

Safety Data

• Hazardous Substances Data: 1279818-81-3(Hazardous Substances Data)

Upstream product

• 75-62-7 Bromotrichloromethane 
• 99-61-6 3-nitro-benzaldehyde 
• 70-23-5 ethyl Bromopyruvate 
• 645-09-0 3-nitrobenzamide 

Downstream Products

• 36841-51-7 (2-(3-nitrophenyl)oxazol-4-yl)methanol 
• 885274-73-7 ethyl 2-(3-aminophenyl)oxazole-4-carboxylate 

Relevant articles and documents

SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS

Disclosed are compounds of Formula (I) or a stereoisomer, a tautomer, or a salt or solvate thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. Also disclosed are pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

A silver-mediated one-step synthesis of oxazoles

A silver-mediated one-step procedure to 2,4-disubstituted and 2,4,5-trisubstituted oxazoles has been developed. The method is complementary to existing technologies, yet provides advantages with regard to simplicity, efficiency, and performance. The silver product can be readily recycled, thus minimizing waste.