1282-40-2

Basic information

• Product Name: BIS(METHYLCYCLOPENTADIENYL)TITANIUM DICHLORIDE
• Synonyms: bis(eta(sup5)-methylcyclopentadienyl)dichlorotitan(iv);dichlorobis(methyl-pi-cyclopentadienyl)-titaniu;BIS(METHYLCYCLOPENTADIENYL)TITANIUM DICHLORIDE;BIS(METHYLCYCLOPENTADIENYL)TITANIUM(IV) DICHLORIDE;BIS-(METHYLCYCLOPENTADIENYL)-DICHLOROTITANIUM(IV);Bis(methylcyclopentadienyl)titanium Dichloride, Recrystalized;5-methylcyclopenta-1,3-diene
• CAS NO: 1282-40-2
• Molecular Formula: C₁₂H₁₄Cl₂Ti
• Molecular Weight: 277.01
• Mol File: 1282-40-2.mol
• Article Data: 12

Chemical Properties

• Melting Point: 220-225 °C
• Boiling Point: 80.4°Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 94.8mmHg at 25°C
• CAS DataBase Reference: BIS(METHYLCYCLOPENTADIENYL)TITANIUM DICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(METHYLCYCLOPENTADIENYL)TITANIUM DICHLORIDE(1282-40-2)
• EPA Substance Registry System: BIS(METHYLCYCLOPENTADIENYL)TITANIUM DICHLORIDE(1282-40-2)

Safety Data

• Hazardous Substances Data: 1282-40-2(Hazardous Substances Data)

Usage

General Description

Bis(methylcyclopentadienyl)titanium dichloride is an organometallic compound that consists of a titanium atom bound to two cyclopentadienyl rings and two chloride ions. It is commonly used as a catalyst in the polymerization of olefins, particularly in the production of polyethylene and polypropylene. The compound is highly reactive and can undergo insertion reactions with unsaturated hydrocarbons, making it a versatile tool in organic synthesis. It is also utilized in the production of specialty chemicals, pharmaceuticals, and other industrial applications. Bis(methylcyclopentadienyl)titanium dichloride is known for its high catalytic activity and selectivity, making it a valuable component in the production of various polymeric materials.

InChI:InChI=1/2C6H7.2ClH.Ti/c2*1-6-4-2-3-5-6;;;/h2*2-5H,1H3;2*1H;/q2*-1;;;+4/p-2

Upstream product

• 7550-45-0 titanium tetrachloride 
• 96-38-8 methylcyclopentadiene 
• 106191-39-3 1,4-{(MeCp)2Ti}2Se₄ 
• 593-89-5 methyldichloroarsane 
• 1270-98-0 cyclopentadienyl titanium(IV) trichloride 
• 10025-67-9 disulfur dichloride 
• 594-42-3 chlorothio-trichloro-methane 
• 14647-23-5 1,2-bis(diphenylphosphino)ethane nickel(II) chloride 
• 90432-13-6 (CH₃C₅H₄)2TiS₄P₂(C₆H₄OCH₃)2 
• 59139-01-4 (η5-methylcyclopentadienyl)dichloridovanadium(IV) 
• 10199-34-5 cis-dichlorobis(triphenylphosphine)platinum(II) 
• 75-44-5 phosgene 
• 31011-57-1 tetrachlorobis(tetrahydrofuran)titanium(IV) 

Downstream Products

• 1282-31-1 (η-5-methylcyclopentadienyl)titanium trichloride 

Relevant articles and documents

Water soluble, hydrolytically stable derivatives of the antitumor drug titanocene dichloride and binding studies with nucleotides

The rate of hydrolysis of the aromatic rings of Cp2TiX2 and the dimethylsubstituted derivatives (MeCp)2TiX2 [X=Cl, O2CCH2NH3Cl], in aqueous solutions at pH 2-8 have been studied

Titanium(IV) carboxylate complexes: Synthesis, structural characterization and cytotoxic activity

Four titanium(IV) carboxylate complexes [Ti(η5-C5H5)2 (O2CCH2SMes)2] (1), [Ti(η5-C5H4Me)2 (O2CCH2SMes)2] (2), [Ti(η5-C5H5)(η5 -C5H4SiMe3)(O2CCH2SMes )2] (3) and [Ti(η5-C5Me5)(O2CCH 2SMes)3] (4; Mes = 2,4,6-Me3C6H2) have been synthesised by the reaction of the corresponding titanium derivatives [Ti(η5-C5H5)2Cl 2], [Ti(η5-C5H4Me) 2Cl2], [Ti(η5-C5H5)(η5 -C5H4SiMe3)Cl2] and [Ti(η5-C5Me5)Cl3] and two (for 1-3) or three (for 4) equivalents of mesitylthioacetic acid. Complexes 1-4 have been characterized by spectroscopic methods and the molecular structure of the complexes 1, 2 and 4 have been determined by X-ray diffraction studies. The cytotoxic activity of 1-4 was tested against tumor cell lines human adenocarcinoma HeLa, human myelogenous leukemia K562, human malignant melanoma Fem-x, and normal immunocompetent cells, that is peripheral blood mononuclear cells PBMC and compared with those of the reference complexes [Ti(η5-C5H5)2Cl 2] (R1), [Ti(η5-C5H4Me)2Cl 2] (R2), [Ti(η5-C5H5)(η5 -C5H4SiMe3)Cl2] (R3) and cisplatin. In all cases, the cytotoxic activity of the carboxylate derivatives was higher than that of their corresponding dichloride analogues, indicating a positive effect of the carboxylato ligand on the final anticancer activity. Complexes 1-4 are more active against K562 (IC50 values from 72.2 to 87.9 μM) than against HeLa (IC50 values from 107.2 to 142.2 μM) and Fem-x cells (IC50 values from 90.2 to 191.4 μM).

The Synthesis of Cyclic Organosulfur Compounds from (C5H4)4Ti2C2S4 by Ligand Transfer Reactions

The tetrathiaoxalate complex Cp4Ti2C2S4 (1) reacts with an equimolar amount of COCl2 to give the blue-green mononuclear complex Cp2TiC2S4CO (4).This reaction is analogous to the known reactions of 1 with SCl2 or S2Cl2.However, when 1 was treated with equimolar amounts of the bifunctional sulfenyl chlorides 1,2-C2H4(SCl)2 (5), 1,3-C3H6(SCl)2 (6) or 1,2-C6H4(SCl)2 (7), the bi- or monocyclic tetrakisdisulfanes C6H8S8 (9b), C8H12S8 (10), and C14H8S8 (11), respectively, were obtained.The X-ray crystal structure analysis of 11*CS2 showed that 11 possesses Ci symmetry with a central exocyclic CC double bond similar to tetrathiafulvalenes: C6H4(μ-S2)2C=C(μ-S2)2C6H4. - Key Words: Titanocene complexes/ Organosulfur ligands/ Ligand transfer/ Organosulfur heterocycles/ Sulfur-sulfur bonds