128405-29-8

Basic information

• Product Name: 2-Amino-6-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinolin-3-yl)-4-phenyl-4H-pyran-3-carboxylic acid ethyl ester
• Synonyms: 2-Amino-6-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinolin-3-yl)-4-phenyl-4H-pyran-3-carboxylic acid ethyl ester
• CAS NO: 128405-29-8
• Molecular Weight: 418.449
• Mol File: 128405-29-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Amino-6-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinolin-3-yl)-4-phenyl-4H-pyran-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinolin-3-yl)-4-phenyl-4H-pyran-3-carboxylic acid ethyl ester(128405-29-8)
• EPA Substance Registry System: 2-Amino-6-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinolin-3-yl)-4-phenyl-4H-pyran-3-carboxylic acid ethyl ester(128405-29-8)

Safety Data

• Hazardous Substances Data: 128405-29-8(Hazardous Substances Data)

Upstream product

• 54289-76-8 3-acetyl-4-hydroxy-1-methyl-2(1H)-quinolone 
• 2025-40-3 ethyl benzylidenecyanoacetate 
• 18706-63-3 4-Hydroxy-6-methyl-5,6-dihydro-2,5-dioxo-2H-pyrano<3,2-c>quinoline 

Relevant articles and documents

Reactions with 2(1H)-quinolinone and coumarine derivatives: New routes to polysubstituted 2(1H)-quinolinone and coumarine derivatives

Whereas 2H-pyrano[3,2-c[quinoline-2,5(6H)-dione (2a) or 3-acetyl-1-methyl-2(1H)-quinolinone (3a) reacted with the benzylidenenitriles 1a-f or a mixture of either malononitrile or ethyl cyanoacetate and aromatic aldehydes in ethanol/piperidine to give 4H-pyran derivatives 8, the reaction of 2b,c or 3b,c with the same reagents afforded 4,6-dihydro-5H-pyrano[3,2-c]quinolin-5-ones 11. Compounds 11 were also prepared from 1a-f and 3d,e,f. Reaction of pyrano[3,2-c]coumarin 2d with 1a yielded 6H,11H-[2]benzopyrano[4,3-c]-[1]benzopyran-6,11-dione (15). Treatment of 17 with aqueous potassium cyanide or hydroxylamine afforded the 2(1H)-quinolinone derivatives 19 and 20 respectively.