128691-93-0

Basic information

• Product Name: Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)-
• Synonyms: 2,2,2-Trifluoro-N-(4-methoxy-2-nitro-phenyl)-acetamide;N-<6-Nitro-4-methoxy-phenyl>-trifluoracetamid;4-methoxy-2-nitrotrifluoroanilide
• CAS NO: 128691-93-0
• Molecular Formula: C9H7F3N2O4
• Molecular Weight: 264.161
• Mol File: 128691-93-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)-(128691-93-0)
• EPA Substance Registry System: Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)-(128691-93-0)

Safety Data

• Hazardous Substances Data: 128691-93-0(Hazardous Substances Data)

Usage

General Description

Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)- is a chemical compound that belongs to the class of acetamides. It has a molecular formula of C9H8F3N3O4 and a molecular weight of 289.17 g/mol. Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)- is characterized by the presence of a trifluoromethyl group and a nitrophenyl group, which make it a versatile building block in organic synthesis. It is commonly used in the pharmaceutical industry for the synthesis of various drugs and pharmaceutical intermediates. Additionally, it has potential applications in the field of agrochemicals, dyes, and pigments. Overall, Acetamide, 2,2,2-trifluoro-N-(4-methoxy-2-nitrophenyl)- is a valuable compound with diverse uses in different industries.

Upstream product

• 332-34-3 2,2,2-trifluoro-N-(4-methoxy-phenyl)-acetamide 
• 104-94-9 4-methoxy-aniline 
• 407-25-0 trifluoroacetic anhydride 
• 96-96-8 4-methoxy-2-nitroaniline 

Downstream Products

• 128897-59-6 N-(2-amino-4-methoxyphenyl)-2,2,2-trifluoroacetoamide 
• 3360-79-0 N-methyl-4-methoxy-2-nitroaniline 
• 182058-27-1 2-(4-Chloro-phenyl)-1-methyl-1H-benzoimidazol-5-ol 
• 182061-08-1 N-(2-Amino-4-methoxy-phenyl)-4-chloro-N-methyl-benzamide 
• 182061-02-5 2-(4-Chloro-phenyl)-1-methyl-3-oxy-1H-benzoimidazol-5-ol 

Relevant articles and documents

Benzimidazole- and benzothiazole-quinones: Excellent substrates for NAD(P)H:quinone oxidoreductase 1

A series of benzimidazole- and benzothiazole-quinones has been synthesized. The ability of these heterocyclic quinones to act as substrates for recombinant human NAD(P)H:quinone oxidoreductase (NQO1), a two-electron reductase upregulated in tumour cells,

A 'one-pot' phase transfer alkylation/hydrolysis of o-nitrotrifluoroacetanilides. A convenient route to N-alkyl o-phenylenediamines

A variety of o-nitrotrifluoroacetanilides undergo a one-pot alkylation/hydrolysis to give N-alkyl o-nitroanilines in 40-94% yield. Dimethylsulfate, benzyl bromide and 1-bromo-propane were used as the electrophiles.

Synthesis of 1-Trifluoroacetyl-3-dialkylaminomethyl-5-monosubstituted Benzimidazoline-2-thiones using Trifluoroacetic Acid as an Acylating Agent

1-Trifluoroacetyl-3-dialkylaminomethyl-5-monosubstituted benzimidazoline-2-thiones have been synthesized from p-substituted anilines which were acetylated with trifluoroacetic acid.The trifluoroacetanilides were nitrated, reduced and cyclised with carbon