128704-85-8 Usage
General Description
(+)-a-Aminomethyl-o-chlorobenzyl alcohol is a chemical compound that combines an aminomethyl group, a chlorobenzyl group, and an alcohol group. It is commonly used as a reagent in organic synthesis and pharmaceutical manufacturing. The compound has potential applications in the creation of pharmaceuticals, particularly in the development of new drugs and medications. It also has the ability to act as a chiral auxiliary in asymmetric synthesis, making it a valuable tool for producing enantiomerically pure compounds. Additionally, (+)-a-Aminomethyl-o-chlorobenzyl alcohol has shown promising results in antiviral and antibacterial activities, making it a versatile and valuable chemical compound in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 128704-85-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,7,0 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 128704-85:
(8*1)+(7*2)+(6*8)+(5*7)+(4*0)+(3*4)+(2*8)+(1*5)=138
138 % 10 = 8
So 128704-85-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClNO/c9-7-4-2-1-3-6(7)8(11)5-10/h1-4,8,11H,5,10H2
128704-85-8Relevant articles and documents
Aminoalcohols II: Preparation of Enantiomerically Pure Pharmacologically Active β-Aminoalcohols
Noe, C. R.,Knollmueller, M.,Gaertner, P.,Fleischhacker, W.,Katikarides, E.
, p. 481 - 494 (2007/10/02)
A synthesis of β-aminoalcohols is described starting from racemic or enantiomerically pure α-hydroxynitriles which were O-protected using enantiomerically pure acetal type protective groups.Reduction with lithium aluminium hydride yielded O-protected β-aminoalcohols.Whenever diastereomeric O-protected cyanohydrins could not be separated, the mixture was reduced and the resulting O-protected aminoalcohols were separated.Removal of the protective group using hydrogen chloride and methanol yielded enantiomerically pure β-aminoalcohols or their corresponding hydrochlorides. - Keywords: 1,2-Amino-alcohols, enantiomerically pure; Lithium aluminium hydride reduction