1287795-39-4Relevant articles and documents
Asymmetric organocatalytic tandem cyclization/transfer hydrogenation: A synthetic strategy for enantioenriched nitrogen heterocycles
Shi, Feng,Tan, Wei,Zhang, Hong-Hao,Li, Mei,Ye, Qin,Ma, Guan-Hua,Tu, Shu-Jiang,Li, Guigen
, p. 3715 - 3726 (2014/01/06)
An asymmetric organocatalytic tandem reaction comprising cyclization/transfer hydrogenation has been established in a compatible and synergistic way, leading to the step-economical synthesis of enantioenriched tetrahydroquinoxalines and dihydroquinoxalinones from readily accessible materials in excellent enantioselectivity of up to >99% ee. This protocol of a one-operation tandem reaction combines the merits of both tandem reactions and asymmetric organocatalysis, providing an efficient strategy for concisely and enantioselectively synthesizing nitrogen heterocycles with biological relevance. Copyright
Convergent asymmetric disproportionation reactions: Metal/Bronsted acid relay catalysis for enantioselective reduction of quinoxalines
Chen, Qing-An,Wang, Duo-Sheng,Zhou, Yong-Gui,Duan, Ying,Fan, Hong-Jun,Yang, Yan,Zhang, Zhang
supporting information; experimental part, p. 6126 - 6129 (2011/06/22)
A convergent asymmetric disproportionation of dihydroquinoxalines for the synthesis of chiral tetrahydroquinoxalines using a metal/Bronsted acid relay catalysis system has been developed. The use of hydrogen gas as the reductant makes the convergent dispr