1292267-27-6Relevant articles and documents
Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) Inhibitors
He, Yuanjun,Kamenecka, Theodore M.,Shin, Youseung,Song, Xinyi,Jiang, Rong,Noel, Romain,Duckett, Derek,Chen, Weimin,Ling, Yuan Yuan,Cameron, Michael D.,Lin, Li,Khan, Susan,Koenig, Marcel,Lograsso, Philip V.
, p. 1719 - 1723 (2011/05/05)
Quinazoline 3 was discovered as a novel c-jun N-terminal kinase (JNK) inhibitor with good brain penetration and pharmacokinetic (PK) properties. A number of analogs which were potent both in the biochemical and cellular assays were discovered. Quinazoline
