129323-74-6Relevant articles and documents
Transport of the highly charged myo-Inositol Hexakisphosphate molecule across the red blood cell membrane: A phase transfer and biological study
Vincent, Stéphane P,Lehn, Jean-Marie,Lazarte, Jaime,Nicolau, Claude
, p. 2825 - 2834 (2002)
To address the problem of delivering highly charged small molecules, such as phytic acid (InsP6 or IHP), across biological membranes, we investigated an approach based on a non-covalent interaction between transport molecule(s) and IHP. Thus, w
Cholesterol Lowering Bile Acid Binding Agents: Novel Lipophilic Polyamines
Thomas, Edward W.,Cudahy, Michele M.,Spilman, Charles H.,Dinh, Dac M.,Watkins, Tommie L.,Vidmar, Thomas J.
, p. 1233 - 1245 (2007/10/02)
A series of novel lipophilic polyamines was synthesized by the sodium cyanoborohydride-mediated reductive amination of various ketones and aldehydes with the polyamine tris(2-aminoethyl)amine.Two of these compounds, N,N-bis-N'-benzyl-1,2-ethanediamine trihydrochloride (36*3HCl) and N,N-bis-N',N'-dimethyl-1,2-ethanediamine (23), are 29 and 24 times more potent than colestipol hydrochloride, respectively, for lowering animal serum cholesterol levels.